Shengzhou Wu Selected Research

serine racemase

1/2021	Overexpression of D-amino acid oxidase prevents retinal neurovascular pathologies in diabetic rats.
10/2018	Loss-of-function mutation of serine racemase attenuates retinal ganglion cell loss in diabetic mice.
11/2017	Serine racemase deficiency attenuates choroidal neovascularization and reduces nitric oxide and VEGF levels by retinal pigment epithelial cells.
1/2016	Loss-of-function mutation of serine racemase attenuates excitotoxicity by intravitreal injection of N-methyl-D-aspartate.
9/2011	Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy.

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Shengzhou Wu Research Topics

Disease

5	Alzheimer Disease (Alzheimer's Disease) 10/2022 - 01/2016
5	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2021 - 09/2011
3	Choroidal Neovascularization 01/2021 - 11/2017
3	Inflammation (Inflammations) 01/2019 - 12/2004
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2016 - 07/2007
1	Insulin Resistance 10/2022
1	Amyloid Plaque 01/2021
1	Gliosis 01/2021
1	Ischemia 11/2019
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2019
1	Diabetes Mellitus 10/2018
1	Schizophrenia (Dementia Praecox) 08/2016
1	Parkinson Disease (Parkinson's Disease) 10/2014
1	Body Weight (Weight, Body) 09/2011
1	Neuroinflammatory Diseases 07/2007

Drug/Important Bio-Agent (IBA)

7	Serine (L-Serine)FDA Link 01/2021 - 07/2007
5	serine racemaseIBA 01/2021 - 09/2011
4	Retinaldehyde (Retinal)IBA 01/2021 - 01/2016
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 11/2017
2	CalciumIBA 01/2020 - 01/2016
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2016 - 10/2014
1	Insulin (Novolin)FDA Link 10/2022
1	C-PeptideIBA 10/2022
1	MicroRNAs (MicroRNA)IBA 12/2021
1	Peptides (Polypeptides)IBA 01/2021
1	Bortezomib (Velcade)FDA Link 01/2021
1	Amyloid (Amyloid Fibrils)IBA 01/2021
1	OccludinIBA 01/2021
1	D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)IBA 01/2021
1	Aspartic Acid (Aspartate)FDA Link 01/2019
1	Protein AggregatesIBA 01/2019
1	Retinal Pigments (Pigments, Visual)IBA 11/2017
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2017
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 08/2016
1	PresenilinsIBA 01/2016
1	Glycoproteins (Glycoprotein)IBA 10/2014
1	Oxidopamine (6 Hydroxydopamine)IBA 10/2014
1	UbiquitinIBA 10/2014
1	CalnexinIBA 10/2014
1	CalreticulinIBA 10/2014
1	Proteasome InhibitorsIBA 10/2014
1	Blood Glucose (Blood Sugar)IBA 09/2011
1	Streptozocin (Streptozotocin)FDA Link 09/2011
1	Glutamic Acid (Glutamate)FDA Link 07/2007
1	Messenger RNA (mRNA)IBA 12/2004

Therapy/Procedure

1	Therapeutics 01/2021
1	Axotomy 11/2019
1	Intravenous Injections 01/2019
1	Intraperitoneal Injections 09/2011